Entebbe, Uganda

Vaccination and alternatives to antimicrobials: why do we still fight vaccine-preventable diseases with antibiotics ?

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Dr. Patrick Bastiaensen of the WOAH Sub-Regional Representation in Nairobi, Kenya, delivering the closing remarks. Picture (c) D. Tegegne (woah) 2025. 

Antimicrobial resistance (AMR) poses a significant global threat to public health, food security and sustainable animal production. The misuse of antimicrobials in the treatment of animal diseases has been one of the main factors driving the emergence and spread of resistant pathogens, rendering antimicrobials ineffective.

Vaccination is one of the most cost-effective interventions we have to prevent animal diseases, protect animal welfare and significantly reduce the use of antimicrobials. It is the best weapon we have against diseases for which vaccines exist!

This is not just the view of WOAH. It is a global commitment, underscored by the recent high-level meeting on AMR, held during the 79th United Nations General Assembly (UNGA), which prioritised prevention and vaccination strategies.

However, we face significant challenges, ranging from limited access to quality vaccines, to the presence of substandard and falsified vaccines, to the underutilisation of these vital tools, particularly in Africa, due to barriers in vaccine development, production, regulation and distribution.

To address these challenges, WOAH, in collaboration with Canada’s International Development Research Centre (IDRC), organised a three-day regional workshop in Entebbe, Uganda, from 28 to 30 October 2025.

The workshop brought together 69 participants (including 22 women, or 32%), who included WOAH focal points for disease notification and veterinary products from 24 English-speaking African countries, representatives from vaccine production laboratories, veterinary drug regulatory authorities, and researchers working on vaccines and alternatives to antimicrobials.

Dr Joseph Nkhoma (Malawi). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

The workshop aimed to:

  • Determine how to strengthen access to vaccines in Africa while supporting technology transfer for local production of vaccines and other non-vaccine alternatives.
  • Review best practices for effective vaccination and assess readiness to use innovative alternatives to antimicrobials.
  • Promote the prioritisation of vaccination and access to quality-assured vaccines as key tools in the fight against AMR and encourage their integration into AMR national action plans.
  • Raise awareness of the research and regulatory frameworks needed for other alternatives to antimicrobials.

The OMSA urges its Members (member countries and territories) to harmonise their national regulations with international standards in order to streamline the marketing authorisations of vaccines and improve access to them. It also stresses the importance of post-vaccination surveillance and the strengthening of the collaboration between governments, industry and research institutions.

To fight AMR in the animal health sector, it is essential to shift from a paradigm focused on treating animal diseases to one focused on preventing them. Vaccination, combined with improved biosecurity and other alternative strategies, is an essential tool for reducing dependence on antimicrobials while protecting animal welfare, health and productivity.

Dr. Nicholas Svitek (ILRI). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Dr Josephine Namayanja (Uganda). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Mr. Aloysius Momo (Liberia). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Dr. Safwat Abdelhameed (Egypt). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Dr. Barbra Bhebhe (Zimbabwe). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Dr Fusya Goma (Zambia). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Dr Abhinashing Kailaysur (Mauritius). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Dr Damaris Mwololo (Kenya). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Dr Zivanai Makoni (Zimbabwe). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Dr Musa Mulongo (ILRI). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Dr Sihle Mdluli (Eswatini). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

The meeting brought together teams of up to two WOAH national focal points from the following countries:

  • Angola
  • Botswana
  • Egypt
  • Ethiopia
  • Eswatini
  • Gambia
  • Ghana
  • Kenya
  • Lesotho
  • Liberia
  • Malawi
  • Mozambique
  • Mauritius

 

 

  • Namibia
  • Nigeria
  • Rwanda
  • Seychelles
  • Sierra Leone
  • Somalia
  • South Sudan
  • Sudan
  • Uganda
  • Zambia
  • Zimbabwe

The West African Health Organisation (WAHO, ECOWAS), the NVRI (Vom), NAFDAC (Abuja), Nigeria and the CVRI (Lusaka) of Zambia participated as observers.

The meeting benefited from the scientific and technical support of several national, regional and international experts and institutions:

  • AU-CDC (Africa CDC)
  • AU-PANVAC
  • Design Biologix
  • FAO (Uganda)
  • GALVmed
  • IDRC (Canada)
  • ILRI
  • STAR-IDAZ (IRC)
  • VMD (UK)
  • WHO (AFRO)

and the AMR and Veterinary Products Department of WOAH in Paris.

The meeting was organised with financial support from Canada and the United Kingdom:

WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda

By prioritising vaccination and other non-vaccine alternatives, we will preserve essential antimicrobials for future generations while ensuring the sustainability of animal production systems.

This workshop was a crucial step towards translating global commitments into concrete, collaborative action at regional and national levels, thereby promoting a healthier future for animals and humans.

Driven by our shared determination regarding the need for vaccination and the use of alternatives to antimicrobials, we have developed a joint roadmap to develop, improve and implement vaccination strategies to ensure a healthier and more resilient future for African livestock and the communities that depend on them.

Download the presentations (1)

Flavie Vial - WOAH - 2024 UN Political Declaration on AMR
Flavie Vial - WOAH - 2024 UN Political Declaration on AMR

PDF - 3.22MB

Gelagay Melesse - PANVAC - Vaccines and their importance in animal disease control and as  alternative to antimicrobial resistance
Gelagay Melesse - PANVAC - Vaccines and their importance in animal disease control and as alternative to antimicrobial resistance

PDF - 2.12MB

Gelagay Melesse - PANVAC - Standardization and quality control of  biological products
Gelagay Melesse - PANVAC - Standardization and quality control of biological products

PDF - 1.88MB

Noel Aineplan - GALVmed - PPP for vaccine delivery and vaccino vigilance: Fostering collaboration between vaccine manufacturers, veterinary services, and farmers.
Noel Aineplan - GALVmed - PPP for vaccine delivery and vaccino vigilance: Fostering collaboration between vaccine manufacturers, veterinary services, and farmers.

PDF - 2.08MB

Download the presentations (2)

Najete Safini - IDRC - IDRC’s Work on Vaccines and Alternatives to Antimicrobials & partnership with WOAH (Innovate)
Najete Safini - IDRC - IDRC’s Work on Vaccines and Alternatives to Antimicrobials & partnership with WOAH (Innovate)

PDF - 3.03MB

Musa Mulongo - ILRI - ILRI’s Work on vaccines and alternatives to Antimicrobials and possible areas of collaboration with WOAH
Musa Mulongo - ILRI - ILRI’s Work on vaccines and alternatives to Antimicrobials and possible areas of collaboration with WOAH

PDF - 3.26MB

Vish Nene - STAR-IDAZ - Recent Innovations in alternatives to antimicrobials and Veterinary Vaccine Technology
Vish Nene - STAR-IDAZ - Recent Innovations in alternatives to antimicrobials and Veterinary Vaccine Technology

PDF - 4.11MB

Angela Buys - Design Biologix - Autogenous vaccines. How can Africa leverage on their production and use?
Angela Buys - Design Biologix - Autogenous vaccines. How can Africa leverage on their production and use?

PDF - 778.00KB

Download the presentations (3)

Suzanne Eckford - VMD - Regulatory Requirements and policies for non-vaccine alternative product approvals for production and use.
Suzanne Eckford - VMD - Regulatory Requirements and policies for non-vaccine alternative product approvals for production and use.

PDF - 344.12KB

Yewande Alimi - Africa CDC - Preventative Approaches bestseller for AMR in Africa - IPC, Access and Vaccines
Yewande Alimi - Africa CDC - Preventative Approaches bestseller for AMR in Africa - IPC, Access and Vaccines

PDF - 1.98MB

Walter Fuller - WHO - Status of Antimicrobial Use Surveillance and Stewardship Activities in the African Region
Walter Fuller - WHO - Status of Antimicrobial Use Surveillance and Stewardship Activities in the African Region

PDF - 1.26MB

Willington Ojong - FAO - Work on vaccination and how countries can leverage on it to improve vaccination strategies for priority animal diseases in animals
Willington Ojong - FAO - Work on vaccination and how countries can leverage on it to improve vaccination strategies for priority animal diseases in animals

PDF - 2.27MB

Visit of the UVRI Facilities in Entebbe. WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Visit of the UVRI Facilities in Entebbe. WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Visit of the UVRI Facilities in Entebbe. WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Visit of the UVRI Facilities in Entebbe. WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Visit of the UVRI Facilities in Entebbe. WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Visit of the UVRI Facilities in Entebbe. WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Download the presentations (4)

Walter Fuller - WHO - Improving Antimicrobial Use in Africa Context and Challenges and Opportunities
Walter Fuller - WHO - Improving Antimicrobial Use in Africa Context and Challenges and Opportunities

PDF - 1.39MB

Najete Safini - IDRC - How can African countries create incentive structures for vaccine development targeting AMR-reduction potential amidst competing country priorities ?
Najete Safini - IDRC - How can African countries create incentive structures for vaccine development targeting AMR-reduction potential amidst competing country priorities ?

PDF - 484.20KB

Noel Aineplan - GALVmed - Reliance and mutual recognition agreements to increase access to veterinary vaccines.
Noel Aineplan - GALVmed - Reliance and mutual recognition agreements to increase access to veterinary vaccines.

PDF - 868.94KB

IDRC Special Event on Promising Research into Non-Vaccine Alternatives to Antimicrobials in Africa

Nicholas Svitek - IDRC - Harnessing bacteriophages for mastitis prevention in goats (Kenya)
Nicholas Svitek - IDRC - Harnessing bacteriophages for mastitis prevention in goats (Kenya)

PDF - 8.68MB

Takele Tefera - IDRC - Novel nanoparticle therapeutics as alternatives to antibiotics to control Escherichia coli bacterial infection in ruminants in Ethiopia
Takele Tefera - IDRC - Novel nanoparticle therapeutics as alternatives to antibiotics to control Escherichia coli bacterial infection in ruminants in Ethiopia

PDF - 1.44MB

Gaymary Bakari - IDRC - Development of COMMI Nanoformulation from Commiphora Plant Resins for Innovative Mastitis Treatment (Tanzania)
Gaymary Bakari - IDRC - Development of COMMI Nanoformulation from Commiphora Plant Resins for Innovative Mastitis Treatment (Tanzania)

PDF - 4.26MB

Ismael Odetokun - IDRC - Developing bacteriocin-rich extract from engineered lactic acid bacteria as an antibiotic alternative in ruminants and aquaculture (Nigeria)
Ismael Odetokun - IDRC - Developing bacteriocin-rich extract from engineered lactic acid bacteria as an antibiotic alternative in ruminants and aquaculture (Nigeria)

PDF - 3.91MB

Dr Jane Lwoyero (WOAH). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Dr Nada Mansour (Sudan). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Dr Margarida Mussimbite (Mozambique). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Dr Mary Manyiel (South Sudan). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Dr Dechassa Tegegne (WOAH). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Dr Odireleng Thololwane (Botswana). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Dr Sati Ngulukun (Nigeria). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Dr Naphtal Mwanziki (Kenya). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) D. Tegegne (woah) 2025

Ms. Heba Farouk (Egypt). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Solomon Kebede Kotu (Ethiopia). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Dr Mustapha Manneh (Gambia). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

Dr Danso Fenteng (Ghana). WOAH Regional Workshop on Vaccination and Alternatives to Antimicrobials (English-speaking Africa) 28 – 30 October 2025 Entebbe, Uganda. Picture (c) P. Bastiaensen (woah) 2025

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